Clinical Effect of Minocycline Hydrochloride Combined with Root Canal Filling in the Treatment of Elderly Patients with Chronic Periodontitis Complicated with Pulp Disease
Objective To explore the clinical effect of minocycline hydrochloride combined with root canal filling in the treatment of elderly patients with chronic periodontitis(CP)complicated with pulp disease.Methods A total of 98 elderly patients with CP complicated with pulp disease admitted to Nanyang Third People's Hospital from October 2020 to October 2022 were selected and divided into a study group(n=49,treated with minocycline hydrochloride combined with root canal filling)and a control group(n=49,treated with root canal filling)using a random number table method.The periodontal index levels,pain degree,and adverse reactions were compared between the two groups.Results After treatment,the gingival index(GI),bleeding index(BI),and plaque index(PLI)decreased in both groups,and the levels of GI,BI,and PLI in the study group were lower than those in the control group,with statistically significant differences(P＜0.05).The visual analog scale(VAS)scores for pain decreased in both groups after treatment,and the VAS scores in the study group were lower than those in the control group,with statistically significant differences(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the study group(6.12%)and the control group(10.20%)(P＞0.05).Conclusion The combination of minocycline hydrochloride and root canal filling in the treatment of elderly patients with CP complicated with pulp disease can improve periodontal index levels,reduce pain degree,and does not increase adverse reactions.
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