Clinical Effect Analysis of Pranoprofen Combined with Sodium Hyaluronate in the Treatment of Dry Eye Syndrome after Glaucoma Surgery
Objective To investigate the clinical effect of pranoprofen combined with sodium hyaluronate in the treatment of dry eye syndrome after glaucoma surgery.Methods A total of 96 patients with dry eye syndrome after glaucoma surgery who were treated at Nanle County People's Hospital from February 2022 to January 2023 were selected and randomly divided into a study group(n=48,treated with pranoprofen combined with sodium hyaluronate)and a control group(n=48,treated with sodium hyaluronate).The clinical efficacy,dry eye symptom scores[Standard Patient Evaluation of Eye Dryness(SPEED)],tear film function[breakup time(BUT),Schirmer's test(SIT),corneal fluorescein staining(CFS)],and incidence of adverse reactions were compared between the two groups.Results The effective treatment rate in the study group(97.92%)was higher than that in the control group(81.25%),with statistically significant differences(P＜0.05).One month after treatment,the SPEED scores in both groups decreased,and the SPEED scores in the study group were lower than those in the control group,with statistically significant differences(P＜0.05).One month after treatment,the BUT and SIT levels in both groups increased,and the CFS scores decreased.The BUT and SIT levels in the study group were higher than those in the control group,and the CFS scores were lower than those in the control group,with statistically significant differences(P＜0.05).The incidence of adverse reactions in the study group(4.17%)was lower than that in the control group(20.83%),with statistically significant differences(P＜0.05).Conclusion The use of pranoprofen combined with sodium hyaluronate in the treatment of patients with dry eye syndrome after glaucoma surgery can improve clinical efficacy,alleviate dry eye symptoms,enhance BUT,SIT,and tear film function,reduce CFS scores,and lower the risk of adverse reactions.It is worthy of application.
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