Analysis of the Efficacy of CT-Guided Pulsed Radiofrequency Combined with Ozone Injection in Treating Postherpetic Neuralgia
Objective To explore the clinical effects of CT-guided pulsed radiofrequency combined with ozone injection for the treatment of postherpetic neuralgia associated with herpes zoster.Methods A retrospective analysis was conducted on 72 patients with herpes zoster treated at Nanyang Central Hospital from January 2022 to September 2023.Patients were divided into three groups based on the duration of their condition:acute group(≤30 days),subacute group(31-90 days),and postherpetic neuralgia group(＞90 days),with 24 patients in each group.Pain levels,sleep quality,rescue medication requirements,and adverse reactions were compared among the three groups after treatment.Results There were no statistically significant differences in pain scores among the three groups before treatment(P＞0.05).After treatment,pain scores decreased in all groups,with the acute and subacute groups showing significantly lower pain scores at 1,3,and 6 months compared to the postherpetic neuralgia group(P＜0.05),while there were no significant differences between the acute and subacute groups(P＞0.05).There were no significant differences in sleep quality scores among the three groups before treatment(P＞0.05).After treatment,sleep quality scores decreased in all groups,with the acute and subacute groups having significantly lower sleep quality scores at 1,3,and 6 months compared to the postherpetic neuralgia group(P＜0.05),while no significant differences were observed between the acute and subacute groups(P＞0.05).The requirement for rescue medication in the acute and subacute groups showed no significant differences(P＞0.05),but the postherpetic neuralgia group had a higher need for rescue medication than the acute and subacute groups,which was statistically significant(P＜0.05).No adverse reactions occurred in any of the groups.Conclusion CT-guided pulsed radiofrequency combined with ozone injection is an effective treatment for postherpetic neuralgia associated with herpes zoster.Early application of this combined treatment can achieve more significant clinical effectiveness and holds promising potential for clinical application.
CT-guidedozone injectionpostherpetic neuralgiavisual analog scale
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