Therapeutic Effects of Qili Qiangxin Capsules Combined with Sacubitril/Valsartan on Elderly Patients with Heart Failure After Acute Myocardial Infarction
Objective To explore the effects of Qili Qiangxin capsule combined with sacubitril/valsartan on cardiac function and serum indicators in elderly patients with heart failure after acute myocardial infarction.Methods A total of 92 patients with heart failure following myocardial infarction admitted to Xinyang Central Hospital from April 2021 to May 2023 were included and randomly divided into two groups of 46 patients each.The control group received treatment with sacubitril/valsartan,while the study group received Qili Qiangxin capsule combined with sacubitril/valsartan.Clinical treatment efficacy,cardiac function,and serum indicators were compared between the two groups.Results The treatment efficacy in the study group was higher than that in the control group,with a statistically significant difference(P＜0.05).The study group had lower left ventricular end-diastolic diameter and end-systolic diameter,and a higher left ventricular ejection fraction compared to the control group,with statistically significant differences(P＜0.05).After treatment,serum levels of N-terminal pro-B-type natriuretic peptide(NT-proBNP),high-sensitivity C-reactive protein(hs-CRP),and tumor necrosis factor-alpha(TNF-α)in the study group were lower than those in the control group(P＜0.05).The 6-minute walk distance in the study group was greater than that in the control group,with a statistically significant difference(P＜0.05).Conclusion Combining Qili Qiangxin capsule with sacubitril/valsartan for elderly patients with heart failure following acute myocardial infarction demonstrates significant efficacy and effectively improves cardiac function and serum indicators.
elderlymyocardial infarctionheart failureQili Qiangxin capsulesacubitril/valsartancardiac function
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