Analysis of Xingnaojing Injection Assisting Emergency Thrombolysis and Anticoagulation Treatment in Acute Cerebral Infarction
Objective To explore the value of auxiliary application of Xingnaojing injection in emergency thrombolysis and anticoagulation treatment for acute cerebral infarction.Methods The study selected 90 patients with acute cerebral infarction admitted to Nanyang Central Hospital from June 2022 to December 2023.They were randomly assigned to a study group(n=45,emergency thrombolysis and anticoagulation treatment+Xingnaojing injection)and a control group(n=45,emergency thrombolysis and anticoagulation treatment).The differences in thrombolytic effect,clinical efficacy,prognosis,serum indicators,and adverse reactions were analyzed.Results Before treatment,there was no significant difference in the National Institutes of Health Stroke Scale(NIHSS)scores between the two groups(P>0.05).After 14 days of treatment,NIHSS scores decreased in both groups,with the study group showing significantly lower scores than the control group(P<0.05).The effective treatment rate in the study group(93.33%)was higher than that in the control group(77.78%),showing a statistically significant difference(P<0.05).Prior to treatment,There was no statistically significant difference in the modified Rankin Rating Scale(mRS)scores between the two groups(P>0.05).After 14 days,mRS scores decreased in both groups,with the study group having lower scores than the control group the difference was statistically significant(P<0.05).There were no significant differences in levels of homocysteine(Hcy)and high-sensitivity C-reactive protein(hs-CRP)between the two groups prior to treatment(P>0.05).After treatment,levels of Hcy and hs-CRP decreased in both groups,with the study group exhibiting lower levels than the control group the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups after treatment(P>0.05).Conclusion The auxiliary application of Xingnaojing injection in emergency thrombolysis and anticoagulation treatment for acute cerebral infarction can improve neurological function,increase the effective treatment rate,exert anti-inflammatory effects,and improve prognosis,demonstrating clinical significance.
Xingnaojing injectionemergencythrombolysis and anticoagulation treatmentacute cerebral infarctionefficacy