首页|糖尿病视网膜病变患者应用生蒲黄汤合泻心汤加减的影响

糖尿病视网膜病变患者应用生蒲黄汤合泻心汤加减的影响

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目的 观察收治糖尿病性视网膜病变患者,实施生蒲黄汤合泻心汤加减干预,探析其在病情改善和安全性的价值。方法 纳入 2021 年 12 月至 2024 年 2 月间由河南省濮阳市安阳地区医院确诊糖尿病视网膜病变患者 120 例资料为研究对象,使用随机数字表分组,实施不同治疗方案。60 例实施西药治疗患者设为对照组,60 例实施西药联合生蒲黄汤合泻心汤加减治疗患者设为观察组。比较组间视功能、视网膜血流动力学、不良反应事件差异。结果 治疗后,观察组最佳矫正视力、视网膜厚度(黄斑区)、视网膜电图振荡电位、眼底出血面积均低于对照组,差异均有统计学意义(P<0。05)。治治疗后,观察组中央静脉回流速度、阻力指数低于对照组,舒张末期流速、收缩期峰值流速、平均血流速度高于对照组,差异均有统计学意义(P<0。05)。两组治疗期间不良反应发生率比较,差异无统计学意义(P>0。05)。结论 在西药治疗基础上实施联合中药方剂生蒲黄汤合泻心汤加减方案治疗糖尿病视网膜病变患者,可改善患者视功能,调整机体血流动力学指标,不会额外增加用药风险,符合临床预期和需求。
Effects of Shengpuhuang Decoction Combined with Xiexin Decoction on Patients with Diabetic Retinopathy
Objective To observe the effects of Shengpuhuang Decoction combined with Xiexin Decoction on patients with diabetic retinopathy and to explore its value in improving the condition and ensuring safety.Methods A total of 120 patients diagnosed with diabetic retinopathy from December 2021 to February 2024 at Anyang Regional Hospital were included as study subjects.They were randomly assigned to different treatment groups.Sixty patients receiving Western medicine were designated as the control group,while sixty patients receiving Western medicine combined with Shengpuhuang Decoction and Xiexin Decoction were designated as the observation group.The differences in visual function,retinal hemodynamics,and adverse reaction events between the two groups were compared.Results After treatment,the best-corrected visual acuity,retinal thickness(macular area),retinal electroretinogram oscillatory potentials,and the area of retinal hemorrhage in the observation group were lower than those in the control group(P<0.05).The observation group also had lower central venous return velocity and resistance index,while showing higher end-diastolic flow velocity,peak systolic flow velocity,and average blood flow velocity compared to the control group,with all differences being statistically significant(P<0.05).There were no significant differences in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion The implementation of a combined treatment plan using Shengpuhuang Decoction and Xiexin Decoction alongside Western medicine for patients with diabetic retinopathy can improve visual function,adjust hemodynamic indicators,and does not increase the risk of medication.This treatment aligns with clinical expectations and needs.

Shengpuhuang DecoctionXiexin Decoctiondiabetic retinopathyhemodynamicsvisual function

杨卓、杨梅、张永选

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河南省濮阳市安阳地区医院 全科医疗科,河南 濮阳 455000

河南省安阳市第五人民医院 肝二科,河南 安阳 456575

生蒲黄汤 泻心汤 糖尿病视网膜病变 血流动力学 视功能

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(12)