摘要
目的 分析甲亢性肝病患者血清学指标检验的临床价值.方法 筛选南阳市第二人民医院 2022 年 5 月至2023 年 12 月收治的 82 例甲亢性肝病患者设定为A组,82 例肝功能正常的甲亢患者设定为B组,82 例院内健康体检人群设定为C组,均检测血清肝功能指标[丙氨酸氨基转移酶(ALT)、直接胆红素(DBIL)、碱性磷酸酶(ALP)、总胆汁酸(TBA)、γ-谷氨酰氨基转移酶(GGT)]、甲状腺功能指标[游离三碘甲状腺原氨酸(FT3)、血清促甲状腺激素(TSH)、游离甲状腺素(FT4)、三碘甲状原氨酸(T3)、甲状腺素(T4)]水平并进行比较.结果 三组肝功能指标、甲状腺功能指标比较,差异有统计学意义(P＜0.05).其中A组GGT、ALT、ALP、TBA、DBIL、TT3、FT3、FT4、TT4、TSH水平均高于B组、C组,B组GGT、ALT、ALP、TBA、DBIL、TT3、FT3、FT4、TT4、TSH水平高于C组,差异有统计学意义(P＜0.05).结论 血清肝功能、甲状腺功能指标水平能有效辅助诊断甲亢性肝病,及时给予患者针对性治疗.
Abstract
Objective To analyze the clinical value of serological indicators in patients with hyperthyroid-related liver disease.Methods A total of 82 patients with hyperthyroid-related liver disease treated at the Second People's Hospital of Nanyang from May 2022 to December 2023 were selected as group A.Group B consisted of 82 hyperthyroid patients with normal liver function,and group C included 82 healthy individuals from hospital health examinations.Serum liver function indicators[alanine aminotransferase(ALT),direct bilirubin(DBIL),alkaline phosphatase(ALP),total bile acids(TBA),gamma-glutamyl transferase(GGT)]and thyroid function indicators[free triiodothyronine(FT3),serum thyroid-stimulating hormone(TSH),free thyroxine(FT4),triiodothyronine(T3),thyroxine(T4)]were measured and compared among the groups.Results There were statistically significant differences in liver function and thyroid function indicators among the three groups(P＜0.05).Specifically,the levels of GGT,ALT,ALP,TBA,DBIL,total T3(TT3),FT3,FT4,total T4(TT4),and TSH in group A were higher than those in groups B and C.Additionally,the levels of GGT,ALT,ALP,TBA,DBIL,TT3,FT3,FT4,TT4,and TSH in group B were higher than those in group C,with statistically significant differences(P＜0.05).Conclusion Serum levels of liver function and thyroid function indicators can effectively aid in the diagnosis of hyperthyroid-related liver disease and facilitate timely,targeted treatment for patients.
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