Predictive Efficacy of Ultrasound Parameters Z-Score and Uterine Artery Blood Flow Parameters for Fetal Growth Restriction in Patients with Gestational Diabetes Mellitus
Objective To explore the predictive efficacy of ultrasound parameters Z-score and uterine artery blood flow parameters for fetal growth restriction (FGR) in patients with gestational diabetes mellitus (GDM). Methods A total of 80 GDM patients admitted to the obstetrics and gynecology department of Zhengzhou Maternal and Child Health Hospital from January 2022 to December 2023 were selected as research subjects. They were divided into FGR group and non-FGR group based on the presence of fetal growth restriction. The ultrasound parameters (abdominal circumference and head-to-abdomen circumference ratio Z-scores) and uterine artery blood flow parameters[ratio of peak systolic velocity to end-diastolic velocity (S/D),resistance index (RI),and pulsatility index (PI)]were compared between the two groups. Receiver operating characteristic (ROC) curves were plotted to investigate the predictive efficacy of ultrasound parameters Z-score and uterine artery blood flow parameters for FGR in GDM patients. Results The differences in fetal abdominal circumference,head-to-abdomen circumference ratio,abdominal circumference Z-score,and head-to-abdomen circumference ratio Z-score between the FGR group and non-FGR group were statistically significant (P＜0.05). The S/D,RI,and PI values in the FGR group were higher than those in the non-FGR group,with statistically significant differences (P＜0.05). The ROC curve showed that the area under the curve for head-to-abdomen circumference ratio Z-score,abdominal circumference Z-score,PI,S/D,and RI were 0.786,0.756,0.747,0.735,and 0.702,respectively,with sensitivity rates of 86.76％,83.21％,81.57％,78.77％,and 76.78％,and specificity rates of 68.79％,67.82％,66.20％,59.76％,and 58.67％,respectively. The combined predictive area under the curve,sensitivity,and specificity were 0.908,92.58％,and 78.96％,respectively. Conclusion The combination of abdominal circumference and head-to-abdomen circumference ratio Z-scores with S/D,RI,and PI parameters has good predictive efficacy for FGR in GDM patients.
维普
万方数据
