Chemical constituents of the fruiting bodies of Ganoderma australe
This research aimed to study the chemical constituents of fruiting bodies of wild Ganoderma australe (Fr.) Pat.,Bull.of the Ganoderma P.Karst.genus.Compounds 1-14 were isolated by the combination of repeated silica gel chromatography,Sephadex LH-20,reversed-phase ODS column,and high performance liquid chromatography.The structures of the compounds were elucidated on the basis of nuclear magnetic resonance spectroscopy,mass spectrometry,IR,and UV spectra.As a result,fourteen compounds,including a new compound (1),were isolated and elucidated as Methyl ganoderenate G (1),Ganoderenic acid G (2),Ganoderenic acid A (3),Methyl ganoderenate A (4),Ganoderenic acid D (5),Ganoderenic acid F (6),Ganoderic acid AP (7),7β,23α-dihydroxy-3,11,15-trioxolanosta-8,20E(22)-dien-26-oic acid (8),Elfvingic acid A(9),3β,5α-dihydroxy-(22E,24R)-ergosta-7,22-dien-6-one(10),p-hydroxybenzoic acid (11),3-hydroxy-4-methoxybenzoic acid (12),9-octadecenoic acid,2,3-dihydroxypropyl ester (13),and β-sitosterol (14).This research isolated nine lanostane-type triterpenoids (Compounds 1-9) from G.australe for the first time.
Ganoderma australefruiting bodychemical constituentstriterpenoidssterolsMethyl ganoderenate G