Effects of turmeric on antioxidant capacity,immune regulation,digestion and absorption function,and microbial community in the small intestine of yellow-feathered broilers
Turmeric possesses antioxidant and immunomodulatory functions and is listed in the"Feed Material Catalog."We aimed to explore the effects of dietary curcumin on the intestinal antioxidant capacity,immune level,digestive and absorptive functions,and microbial community of yellow-feathered broilers.Four hundred one-day-old yellow-feathered broilers were randomly divided into four groups:blank group,curcumin group,0.5％turmeric group,and 1％turmeric group(8 replicates per group,10 broilers per replicate).Experimental diets included 150 mg/kg curcumin,5 g/kg turmeric,and 10 g/kg turmeric.Results showed that:(1)Compared with the blank group,curcumin,0.5％turmeric powder,and 1％turmeric powder increased the activity of superoxide dismutase(T-SOD),glutathione peroxidase(GSH-Px),and total antioxidant capacity(T-AOC)in duodenum,jejunum,and ileum tissues to varying degrees and decreased the content of malondialdehyde(MDA)in these tissues(P＜0.05).(2)Compared with the blank group,turmeric significantly increased the contents of β-defensin and SlgA in the intestines of yellow-feathered broilers(P＜0.05).(3)On day 28,curcumin significantly increased the activities of lactase,sucrase,amylase,lipase,and trypsin(P＜0.05).On day 28,0.5％turmeric significantly increased the activities of maltase,lactase,amylase,lipase,and trypsin(P＜0.05).On day 28,1％turmeric significantly increased the activities of lactase,lipase,and trypsin(P＜0.05).On day 70,both 0.5％turmeric and 1％turmeric significantly increased the activity of lipase(P＜0.05).(4)Compared to the blank group,curcumin,0.5％turmeric powder,and 1％turmeric powder upregulated the mRNA expression levels of SGLT1,GLUT2,and PePT1 in the duodenum,jejunum,and ileum of yellow-feathered broilers(P＜0.05).(5)Compared with the blank group,curcumin significantly reduced the relative abundance of Anaerobic Clavuli at 28 days of age;0.5％turmeric significantly reduced the relative abundance of Intestinimonas;and 1％turmeric significantly reduced the relative abundance of Monoglobus(P＜0.05).Curcumin significantly increased the relative abundance of Clostridium in the cecum at 70 days of age,and 1％turmeric significantly increased the abundance of Gordonella(P＜0.05).These results indicate that curcumin and turmeric powder can improve the intestinal antioxidant capacity of yellow-feathered broilers,regulate intestinal immune function,enhance nutrient digestion and absorption,alter the cecal microbial structure,and improve intestinal health and overall quality of yellow-feathered broilers.The optimal dose of turmeric was 10 g/kg.
turmericcurcuminyellow feathered broilerantioxidationdigestion and absorptionmucosal immunitymicrobial community
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