Design,Implementation,and Validation of an Intelligent Pump for Microfluidic Chip State Perception
An intelligent pump based on the concept of"actuator-as-sensor"is proposed to meet the requirements of real-time prediction of internal fluid state and workflow control in microfluidic chip.The proposed intelligent pump system,working principle,and workflow are introduced,and the requirements for testing microfluidic chip and state prediction are analyzed.A pressure signal processing process is established,after processing the pressure signal,effective time-domain features are extracted for state prediction training.Verification experimentals on the working status of the microfluidic chip are conducted,and the experimentals show that the predicted results of magnetic bead ball redissolution and freeze dried ball redissolution by the intelligent pump are consistent with the actual measurement and biological experimental results,verifying the effectiveness of the intelligent pump system.
万方数据
维普
