基于MCNPX的重离子治癌相关问题研究
MCNPX-based Study on the Issues Related to Heavy Ion Cancer Therapy
刘源源 1吉尚戎 2李金阳 3骆鹏 3张晖 3李强3
作者信息
- 1. 兰州大学生命科学学院,兰州 730000;中国科学院近代物理研究所,兰州 730000
- 2. 兰州大学生命科学学院,兰州 730000
- 3. 中国科学院近代物理研究所,兰州 730000
- 折叠
摘要
利用MCNPX模拟计算了医用重离子加速器示范装置(HIMM)上提供的碳离子束在水中的深度剂量分布,并与在HIMM装置上实验测量得到相应能量碳离子束的深度剂量分布进行比较,发现模拟结果与实验测量结果相符合,验证了MCNPX用于重离子输运模拟的准确性.开发了基于射线追踪技术的解析传输接口软件RTIM和基于PYDICOM的DCVM软件,将存储在DICOM文件中的补偿器信息和患者CT图像信息转化为MCNPX可识别的构造实体表示法信息,从而实现了在MCNPX中对重离子TPS产生的补偿器和患者CT图像建模.这些研究为利用MCNPX模拟HIMM被动式束流配送系统构形后的重离子束流在患者体内的剂量分布奠定了基础.
Abstract
The depth-dose distributions of different energy carbon ions provided by the demonstration facility of Heavy Ion Medical Machine (HIMM) in tissue-like medium water were calculated using the MCNPX Monte Carlo simulation code. The results derived from the simulation calculations were compared with those measured in the facility of HIMM and showed good agreement with the bexperimental data. Therefore, the usability of MCNPX for heavy ion transportation in tissue-like medium is verified. The present work also developed a parsed script transfer interface for MCNPX-(CSG) simulation based on ray casting technology and DCVM (Dose Calculation Viewer for MCNPX) code based on the PYDICOM code to convert the DICOM files of compensator and CT phantoms to corresponding CSG files that can be identified by MCNPX. Then modeling of the compensator and CT phantoms of HIMM in MCNPX was successfully performed. The present work provides a basis for MCNPX simulation for the dose distribution of carbon ions shaped by HIMM passive beam distribution system in patient date patient based on CT images.
关键词
重离子治癌/MCNPX/构造实体表示法/蒙特卡罗模拟/CTKey words
heavy ion cancer therapy/MCNPX/CSG/Monte Carlo simulation/CT引用本文复制引用
基金项目
国家重点研发计划资助项目(2016YFC0904700)
国家科技支撑计划资助项目(2015BAI01B11)
国家自然科学基金资助项目(11075191)
出版年
2017
NETL
NSTL
维普
万方数据