Detection and Analysis of Sulfachloropyrazines and Doxycyclines Residues in Chicken Tissue
After the yellow-feathered broilers of the same-day age were fed with double doses of sulfachloropyrazines or doxycyclines in drinking water,the metabolic residual changes of two types of drugs in chicken tissue during different withdrawal periods were detected,aiming to provide a theoretical basis for promoting healthy poultry breeding and scientifically formulating drug withdrawal period.In the experiment,the yellow-feathered broilers of 90-day-old were selected and randomly divided into 3 groups of 50 chickens in each group,including control group,sulfachloropyrazine drug group and doxycycline drug group.The results showed as follows:no drug residue was detected in control group;In the sulfachloropyrazine group,the drug residues in chicken chest muscles at days 1,4,7 and 11 after withdrawal were(0.034 2±0.021 63)mg/kg,(0.013 4±0.002 12)mg/kg,(0.012 1±0.001 89)mg/kg and(0.008 5±0.001 41)mg/kg,respectively;In the doxycycline group,the drug residues in chicken chest muscles at 7,14,21,28 and 33 days after drug withdrawal were(0.139 5±0.031 61)mg/kg,(0.029 9±0.022 59)mg/kg,(0.010 3±0.003 44)mg/kg,(0.007 7±0.001 12)mg/kg and(0.006 4±0.000 29)mg/kg,respectively.The study concluded that after double doses of sulfachloropyrazines or doxycyclines were administered,sulfachloropyrazine residues were still present on the 11th day of the drug withdrawal period,and doxycycline residues on the 33th day.