首页|新疆某规模羊场主要消化道线虫对阿苯达唑的抗药性检测

新疆某规模羊场主要消化道线虫对阿苯达唑的抗药性检测

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为探讨新疆某规模场羊主要消化道线虫对阿苯达唑的抗药性情况,选择新疆某规模化养殖场内发生消化道线虫病的60只羊作为试验对象,随机分为4组,试验组A为未经任何药物治疗的对照组,试验组B、C、D分别使用剂量为5、10、15 mg/kg阿苯达唑进行治疗,检测投药14 d羊粪便中捻转血矛线虫、细颈线虫、马歇尔线虫、奥斯特线虫等主要消化道线虫的虫卵数及虫卵减少率。结果表明,各试验组捻转血矛线虫、马歇尔线虫、细颈线虫的虫卵减少率均显著高于对照组(P<0。05),试验组C和试验组D奥斯特线虫的虫卵减少率均显著高于对照组和试验组B(P<0。05),且随着投药量的增加,捻转血矛线虫、马歇尔线虫、奥斯特线虫的虫卵数减少率也随之相应显著增高。试验组D的4种主要消化道线虫的虫卵减少率均显著高于其它各组(P<0。05)。新疆某规模场羊主要消化道线虫对阿苯达唑无明显的抗药性,且15 mg/kg阿苯达唑治疗效果良好,这为本地区羊消化道线虫病的科学防治工作提供了参考依据。
Detection of the Resistance of Major Gastrointestinal Nematodes in Sheep in Xinjiang to Albendazole
To explore the resistance of major gastrointestinal nematodes in sheep in Xinjiang to albendazole.Sixty sheep with gastrointestinal nematode disease in a large-scale breeding farm in Xinjiang region were selected as the experimental subjects and randomly divided into four groups.Experimental group A was a control group without any drug treatment,while experimental groups B,C,and D were treated with doses of 5 mg/kg,10 mg/kg,and 15 mg/kg of albendazole,respectively.After 14 days of treatment,the feces of sheep were tested for Haenorhabditis,nematodes,and Marshall's nematodes The number of eggs and egg reduction rate of major gastrointestinal nematodes such as Osterhabditis.The result shows:The egg reduction rates of C.Haemonchus contortus,C.Marshall and C.tenuiformis in each experimental group were significantly higher than those in the control group(P<0.05),the egg reduction rate of AOSTE nematode in Test Group C and Test Group D was significantly higher than that in control group and test group B(P<0.05),the egg reduction rates of C.Haemonchus contortus,C.Marshall and C.Aoste were also significantly higher.The egg reduction rates of the four main digestive tract nematodes in group D were significantly higher than those in other groups(P<0.05).The main gastrointestinal nematodes in sheep in Xinjiang region have no significant resistance to albendazole,and the treatment effect of 15 mg/kg albendazole is good.This provides a reference for the scientific prevention and control of sheep gastrointestinal nematode disease in this region.

gastrointestinal tractnematodealbendazoledrug resistance

丁剑、马站、张丹、马力克·艾则孜

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新疆维吾尔自治区动物疾病预防控制中心,新疆 乌鲁木齐 830000

消化道 线虫 阿苯达唑 抗药性

新疆维吾尔自治区自然科学基金

2021D01B76

2024

现代畜牧科技
黑龙江省畜牧研究所

现代畜牧科技

影响因子:0.066
ISSN:2095-9737
年,卷(期):2024.(6)