Detection of the Resistance of Major Gastrointestinal Nematodes in Sheep in Xinjiang to Albendazole
To explore the resistance of major gastrointestinal nematodes in sheep in Xinjiang to albendazole.Sixty sheep with gastrointestinal nematode disease in a large-scale breeding farm in Xinjiang region were selected as the experimental subjects and randomly divided into four groups.Experimental group A was a control group without any drug treatment,while experimental groups B,C,and D were treated with doses of 5 mg/kg,10 mg/kg,and 15 mg/kg of albendazole,respectively.After 14 days of treatment,the feces of sheep were tested for Haenorhabditis,nematodes,and Marshall's nematodes The number of eggs and egg reduction rate of major gastrointestinal nematodes such as Osterhabditis.The result shows:The egg reduction rates of C.Haemonchus contortus,C.Marshall and C.tenuiformis in each experimental group were significantly higher than those in the control group(P<0.05),the egg reduction rate of AOSTE nematode in Test Group C and Test Group D was significantly higher than that in control group and test group B(P<0.05),the egg reduction rates of C.Haemonchus contortus,C.Marshall and C.Aoste were also significantly higher.The egg reduction rates of the four main digestive tract nematodes in group D were significantly higher than those in other groups(P<0.05).The main gastrointestinal nematodes in sheep in Xinjiang region have no significant resistance to albendazole,and the treatment effect of 15 mg/kg albendazole is good.This provides a reference for the scientific prevention and control of sheep gastrointestinal nematode disease in this region.