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肠道黏膜中的益生菌及其在畜牧业中的应用

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肠黏膜免疫系统是一个由免疫细胞、信号分子和屏障结构组成的高度专业化的网络,旨在保护宿主免受病原体入侵,同时保持对有益和共生微生物的耐受性.益生菌广泛存在于动物胃肠道中,是有益于宿主健康的活性微生物,以营养素以及定植位点的竞争方式,抑制有害细菌增殖,调节肠道菌群结构、代谢和免疫.近年,益生菌对肠道和健康的影响及对一些疾病的治疗作用日益受到重视,另外,益生菌作为改善畜牧业生产效率、保障动物健康和减少抗生素依赖的重要工具,其在畜牧业中的应用及其研究进展引起广泛的研究兴趣和实践探索.该文将从益生菌的种类和特性、调控肠道黏膜屏障功能、调控肠道黏膜免疫、研究现状及产业化应用前景等方面进行综述,增进了解益生菌作为肠道健康的免疫调节剂在畜牧业中的应用潜力.以期为益生菌在畜牧业上的合理开发应用提供参考.
Probiotics in Intestinal Mucosa and its Application in Animal Husbandry
The intestinal mucosal immune system is a highly specialized network composed of immune cells,signaling molecules,and barrier structures.Its primary function is to protect the host from pathogenic invasions while maintaining tolerance to beneficial and symbiotic microorganisms.Probiotics,which are active microorganisms beneficial to the host's health,are widely present in the gastrointestinal tract of animals.They inhibit the proliferation of harmful bacteria by competing for nutrients and colonization sites,thereby regulating the gut microbiota structure,metabolism,and immunity.In recent years,the impact of probiotics on intestinal health and their therapeutic role in certain diseases have gained increasing attention.Furthermore,as an important tool for improving production efficiency in animal husbandry,ensuring animal health,and reducing antibiotic dependency,the application and research progress of probiotics in the livestock industry have sparked widespread research interest and practical exploration.This article will provide an overview of the types and characteristics of probiotics,their regulation of intestinal mucosal barrier function,and mucosal immunity,as well as the current state of research and prospects for industrial application.The aim is to enhance understanding of the potential of probiotics as immunomodulators for gut health in the livestock industry and to offer a reference for their rational development and application in animal husbandry.

probioticsintestinal mucosal barrierintestinal mucosal immunityanimal husbandry

杨倩

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贵州省息烽县农业农村局,贵州 贵阳 550000

益生菌 黏膜屏障 黏膜免疫 畜牧

贵州省科技成果转化一般项目

黔科合成果[2024]一般104号

2024

现代畜牧科技
黑龙江省畜牧研究所

现代畜牧科技

影响因子:0.066
ISSN:2095-9737
年,卷(期):2024.(7)
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