基因编辑技术在牛羊育种中的应用
Application of Gene Editing Technology in Cattle and Sheep Genetic Breeding
朱元芳 1韩永胜 1张建胜 1王洪宝 1李伟 1丁得利 1王艳菲 1林秀蔚 1李青莹 1李平 1丁丽艳 1江波涛 1南景东1
作者信息
- 1. 黑龙江省农业科学院畜牧兽医分院,黑龙江 齐齐哈尔 161005
- 折叠
摘要
基因编辑技术是一种通过修改生物体基因组来改变其遗传性状的技术手段.基因编辑育种一般通过ZFN技术、TALEN技术、CRISPR/Cas系统等基因编辑技术,精确改变动物的DNA序列,继而产生带有目的性状的动物,从而实现对生物体的遗传特性的改良和优化.利用基因编辑技术,可以对具有与生产力相关的基因的牛羊进行编辑与修饰,提高牛羊生产力以应对气候变化或特定疾病.该文主要综述基因编辑技术简介以及该技术在牛羊育种上的应用研究进展,以期基因编辑技术推动牛羊遗传育种在畜牧业上的可持续发展提供参考.
Abstract
Gene editing technology is a technical means to change the genetic traits of organisms by modifying their genomes.Gene editing breeding generally uses ZFN technology,TALEN technology,CRISPR/Cas system and other gene editing technologies to accurately change the DNA sequence of animals,and then produce animals with target traits,so as to improve and optimize the genetic characteristics of organisms.Using gene editing technology,cattle and sheep with genes related to productivity can be edited and modified to improve the productivity of cattle and sheep to cope with climate change or specific diseases.Therefore,this paper mainly reviews the introduction of gene editing technology and the research progress of its application in cattle and sheep breeding,in order to provide reference for gene editing technology to promote the sustainable development of cattle and sheep genetic breeding in animal husbandry.
关键词
基因编辑/育种/生产力Key words
genome editing technology/breeding/productivity引用本文复制引用
基金项目
肉牛牦牛产业技术体系(CARS-37)
黑龙江省农业科技创新跨越工程农业关键技术科技创新重点攻关项目(CX23GG07)
黑龙江省外向型农业产业技术协同创新体系()
黑龙江省现代农业产业技术协同创新推广体系建设项目(黑农厅函[2021]1492号)
&&(ZNKT-202215)
出版年
2024
国家科技期刊平台
NSTL
万方数据