Research Progress on Drugs and Vaccines for Treating Porcine Epidemic Diarrhea
Porcine Epidemic Diarrhea Virus(PEDV)is one of the important pathogenic microorganisms that threaten the development of the pig farming industry,PEDV can rapidly spread in pig herds,causing widespread infection and outbreaks of porcine epidemic diarrhea(PED).Infected pig herds exhibit varying degrees of clinical symptoms with age,with symptoms particularly evident in newborn piglets.PEDV can damage the digestive system of infected piglets,causing clinical symptoms such as loss of appetite,vomiting,diarrhea,and dehydration.Moreover,the mortality rate of piglets with PEDV is extremely high,and the large number of deaths in piglets causes extremely serious economic losses to the pig breeding industry.At present,the main means of preventing this disease are biosafety prevention and control,as well as vaccine immunization.Drugs that have an inhibitory effect on PEDV are still actively being developed.Currently,most of the inhibition of PEDV by drugs occurs before cell infection with viruses,such as lycopene Griffithsin(GRFT).This article elaborates on the drugs that have shown certain inhibitory effects on PEDV in experiments,and briefly summarizes the research progress of PED vaccines.
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维普
