首页|深圳市男男性行为者HIV暴露后预防的使用:一项系列横断面研究

深圳市男男性行为者HIV暴露后预防的使用:一项系列横断面研究

Utilization of post-exposure prophylaxis among MSM in Shenzhen:A serial cross-sectional study

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目的 分析2020-2022年深圳市MSM的nPEP使用情况及其影响因素.方法 2020年 1月至2022年12月,在深圳市通过与社会组织合作招募MSM开展问卷调查,收集人口学、行为学以及nPEP使用等信息.采用x2检验和Logistic回归分析nPEP使用的影响因素.结果 共2 900名研究对象纳入分析,2020-2022年深圳市MSM中三年的nPEP使用率依次为7.00%(55/787)、5.00%(59/1 183)和5.59%(52/930).多因素Logistic回归结果显示:有药物滥用(aOR=1.720,95%CI:1.242~2.381)、近一年在诊所或男同场所接受艾滋病相关服务(aOR=1.741,95%CI:1.068~2.836)、有启动 PrEP 的意愿(aOR=3.299,95%CI:2.256~4.832)、过去一年确诊患有性传播疾病(aOR=1.849,95%CI:1.139~3.000)、有做包皮环切术的历史(aOR=1.591,95%CI:1.029~2.459)的MSM使用nPEP的概率更高,而有固定性伴侣的 MSM(aOR=0.532,95%CI:0.375~0.755)、有套肛交性行为(aOR=0.377,95%CI:0.230~0.619)使用 nPEP 的概率更低.结论 2020-2022年深圳市MSM的nPEP使用率不高,有必要开展针对性的教育宣传,重点关注有固定性伴侣和有套肛交性行为的人群,提高nPEP使用率.
Objective To analyze the utilization of non-occupational post-exposure prophylaxis(nPEP)among men who have sex with men(MSM)in Shenzhen from 2020 to 2022,and its influencing factors.Methods From January 2020 to December 2022,a questionnaire survey was conducted in Shenzhen City by recruiting MSM in collaboration with social organizations,and demographic,behavioral,and PEP utilization information were collected.The x2 test and logistic regression were used to analyze the influencing factors of PEP use.Results A total of 2 900 respondents were included,and the annual PEP utilization rates among MSM in Shenzhen City from 2020 to 2022 were 7.00%(55/787),5.00%(59/1 183),and 5.59%(52/930),respectively.Multivariate logistic regression results showed that MSM with substance abuse(aOR=1.720,95%CI:1.242-2.381),receipt of HIV-related services at a clinic or gay men's establishment in the past year(aOR=1.741,95%CI:1.068-2.836),willingness to initiate pre-exposure prophylaxis(PrEP)(aOR=3.299,95%CI.2.256-4.832),a diagnosis of a sexually transmitted disease in the past year(aOR=1.849,95%CI:1.139-3.000),a history of circumcision(aOR=1.591,95%CI:1.029-2.459)had a higher probability of using nPEP,while MSM with a regular sexual partner(aOR=0.532,95%CI:0.375-0.755),and those with condom anal sex(aOR=0.377,95%CI:0.230-0.619)were less likely to use nPEP.Conclusions PEP utilization among MSM in Shenzhen is relatively low from 2020 to 2022.It is necessary to carry out targeted educational campaigns,focusing on those with regular sexual partners and condom anal sex,to increase PEP utilization rate.

HIVnon-occupational post-exposure prophylaxis(nPEP)men who have sex with men(MSM)influencing factors

戴德磊、杨梓杰、张燕、谭唯、杨峥嵘、刘少础、谢炜、卫兰、李思美、袁苑、袁小洪、唐虎、朱悦、赵锦

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汕头大学公共卫生学院,广东汕头 515063

深圳市疾病预防控制中心,广东深圳 518000

北京大学,北京 100083

中山大学公共卫生学院,广州 510080

山西医科大学公共卫生学院,山西太原 030607

南方医科大学,广州 510515

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艾滋病病毒 非职业暴露后预防 男男性行为者 影响因素

国家自然科学基金深圳市医学重点学科建设经费深圳市医疗卫生三名工程

82373651SZXK064SZSM202311015

2024

中国艾滋病性病
中国性病艾滋病防治协会

中国艾滋病性病

CSTPCD北大核心
影响因子:1.292
ISSN:1672-5662
年,卷(期):2024.30(1)
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