Comparison of two intervention methods in the sexual partner of patients infected with urogenital chlamydia:A meta-analysis
Objective To systematically compare the acceptability and effectiveness of partner notification(PN)and expedited partner therapy(EPT)among patients with urogenital chlamydia infection.Methods Literatures on PN and EPT among patients infected with urogenital chlamydia were retrieved from PubMed,Cochrane Library,GeenMedical,China National Knowledge Internet(CNKI),VIP Chinese Journal Service Platform,and Wanfang Data Knowledge Service Platform from 2013 to 2023.The Cochrane Handbook for Systematic Reviews of Interventions was applied to evaluate literature quality,and RevMan v.5.4 software was used to perform meta-analyses.Results A total of 12 literatures were included and 4 456 cases were reviewed.There was no significant difference in index patients'acceptance rate between PN and EPT(RR=1.13,95%CI:0.88-1.45,P=0.33),whereas EPT was more easily accepted in male index patients or in areas where EPT was legal.Partners of index patients were more likely to accept EPT(RR=2.36,95%CI:1.67-3.34,P<0.000 01).There was no statistically significant difference in the re-infection rate between PN and EPT(RR=0.81,95%CI:0.63-1.06,P=0.12).Conclusions Regarding sexual partner intervention strategies,compared to PN,EPT is more likely to be accepted in male index patients and index patients in areas where EPT is legal.However,no significant effect is found on the rate of re-infection with Chlamydia trachomatis among index patients.
partner notification(PN)expedited partner therapy(EPT)acceptance ratere-infection of Chlamydia trachomatis