首页|2015-2022年我国VCT门诊新报告HIV感染者晚发现趋势分析

2015-2022年我国VCT门诊新报告HIV感染者晚发现趋势分析

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目的 了解2015-2022年我国VCT门诊新报告HIV感染者晚发现情况和变化趋势.方法 通过中国艾滋病综合防治基本信息系统获取2015-2022年VCT门诊新报告HIV感染者信息.利用Joinpoint 回归模型计算VCT门诊新报告感染者晚发现比例的年度变化百分比(APC)和平均年度变化百分比(AAPC)并进行时间趋势检验.以2015-2022年VCT门诊报告HIV感染者年龄构成比例为标准,计算不同人群的年龄标准化晚发现比例(ASPLD).结果 2015-2022年VCT门诊新报告HIV感染者256 098例,以2019年为转折点新报告感染者数量呈现先上升后下降的趋势.2015-2022年VCT门诊新报告HIV感染者的晚发现比例为58.19%(149 019/256 098),晚发现比例总体呈上升趋势(AAPC=1.6%,95%CI:1.2%~2.0%,P<0.05).晚发现比例随着年龄的增加逐渐升高.≥60岁年龄组感染者的晚发现比例为72.59%,无显著变化趋势(P>0.05).18~24年龄组的晚发现比例为44.04%,上升速度最快(AAPC=2.5%,95%CI:1.7%~3.2%,P<0.05).经异性性行为感染的男性感染者ASPLD为60.09%.经异性性行为感染的女性感染者ASPLD为55.11%,呈上升趋势(AAPC=0.9%,95%CI:0.1%~2.6%,P<0.05).结论 我国VCT门诊新报告HIV感染者中,≥60岁感染者、经异性性行为感染的男性感染者晚发现比例总体水平较高,女性感染者晚发现比例持续上升.晚发现仍然是我国HIV防治工作中的重要挑战.未来应完善和优化HIV检测策略;加强针对老年人群的艾滋病知识宣传,促进有感染风险的老年人接受HIV检测;开展针对女性人群的HIV检测宣传.
Analysis of late diagnosis trends of HIV cases reported by VCT clinics in China,2015-2022
Objective To understand the trends of late diagnosis among new HIV cases reported by voluntary counselling and testing(VCT)clinics in China between 2015 and 2022.Methods Data on new HIV cases reported by VCT clinics during the period was extracted from the HIV/AIDS Comprehensive Response Information Management System.Using the Joinpoint regression model,the annual percent change(APC)and average annual percent change(AAPC)in the proportion of late diagnosis were calculated,and a time trend analysis was conducted.The age-standardized proportion of late diagnosis(ASPLD)was calculated for various populations using the age distribution of VCT-reported cases from 2015 to 2022 as the standard.Results A total of 256 098 adult HIV cases were reported by VCT clinics from 2015 to 2022.While the number of cases initially increased until 2019,and it started declining thereafter.Overall,the proportion of late diagnosis among these cases was 58.18%(149 019/256 098),exhibiting a statistically significant upward trend overall(AAPC=1.6%,95%CI:1.2%-2.0%,P<0.05).Notably,the proportion of late diagnosis increased with age.The highest proportion of 72.59%was observed among cases aged 60 years and older,but with no significant trend(P>0.05).Conversely,the fastest rate of increase(AAPC=2.5%,95%CI:1.7%-3.2%,P<0.05)was seen in the 18-24 age group,with a late diagnosis proportion of 44.04%.Among sexually transmitted cases,the ASPLD was higher for males(60.09%)compared to females(55.11%).While the latter group showed a rising trend(AAPC=0.9%,95%CI:0.1%-2.6%,P<0.05).Conclusions Among new HIV cases reported by VCT clinics in China,late diagnosis was conccrningly prevalent in males aged 60 and older and in those infected through heterosexual transmission,particularly females,where the proportion continues to rise.This highlights the need for reinforced HIV testing strategies,targeted AIDS education campaigns and specific testing initiatives for the elderly,as well as strengthened testing and publicity aimed at female population,to effectively address the persistent challenge of late diagnosis in China's HIV prevention and control efforts.

HIV/AIDSvoluntary counselling and testing(VCT)infection statuslate diagnosis

刘毅、苏容、李东民、韩孟杰

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中国疾病预防控制中心性病艾滋病预防控制中心,北京 102206

艾滋病病毒/艾滋病 自愿咨询检测 感染状况 晚发现

国家科技重大专项

2017ZX10201101-002-006

2024

中国艾滋病性病
中国性病艾滋病防治协会

中国艾滋病性病

CSTPCD北大核心
影响因子:1.292
ISSN:1672-5662
年,卷(期):2024.30(2)
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