首页|HIV社交网络与分子传播网络融合研究的进展

HIV社交网络与分子传播网络融合研究的进展

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构建社交网络已成为HIV感染诊断和提供预防服务中的重要依据.同时,随着基因组测序技术的快速进展以及HIV耐药数据大量积累,基于病毒序列分析的HIV分子传播网络在监测HIV传播增长簇、识别HIV感染的高风险个体以及确定HIV传播风险因素上的优势也引起了专家学者们的关注.当分子传播网络与传统的社交网络进行融合应用时,可以为基于分子簇的靶向干预提供关键信息,可将有限的干预资源引至"HIV传播热点"指导靶向干预.本文综述了HIV社交网络和分子传播网络两种方法各自的优势和局限性、目前二者融合的主要方式及效果,为更高效地利用公共卫生资源开展艾滋病精准防控、遏制HIV传播提供新的思路.
Research progress on the integration of HIV social networks and molecular transmission networks
The construction of social networks has become a crucial basis for HIV infection diagnosis and the provision of preventive services.Concurrently,with the rapid advances in genome sequencing technology and a substantial amount of HIV drug resistance data,the advantages of HIV molecular transmission networks based on viral sequence analysis in monitoring HIV transmission growth clusters,identifying high-risk individuals for HIV infection,and determining HTV transmission risk factors have also attracted the attention of experts and scholars.When the molecular transmission network is integrated with the traditional social network,it can provide key information for targeted intervention based on molecular clusters,redirecting limited intervention resources to"HIV transmission hotspots"to guide targeted intervention.This article reviews the advantages and limitations of the two methods of HIV social networks and molecular transmission networks,as well as the current approaches and effects of their fusion,providing new insights for more efficiently utilizing public health resources to conduct precise control of AIDS and curb the spread of HIV.

HIVsocial networksmolecular transmission networksintegrationtargeted intervention

尹晓伊、赵彬、钟平、韩晓旭

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传染病重症诊治全国重点实验室国家卫生健康委艾滋病防治重点实验室国家医学检验临床医学研究中心中国医科大学附属第一医院,沈阳 110001

艾滋病病毒 社交网络 分子传播网络 融合 靶向干预

国家重点研发计划(十四五)

2022YFC2305201

2024

中国艾滋病性病
中国性病艾滋病防治协会

中国艾滋病性病

CSTPCD北大核心
影响因子:1.292
ISSN:1672-5662
年,卷(期):2024.30(2)
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