Factors influencing the timeliness of antiretroviral therapy initiation among newly diagnosed HIV/AIDS cases in Anhui Province(2017-2022)
Objective This study aimed to investigate the status and factors influencing the timely initiation of combination antiretroviral therapy(cART)among newly diagnosed HIV/AIDS cases in Anhui Province from 2017 to 2022.Methods Data on newly diagnosed HIV/AIDS cases in Anhui Province from 2017 to 2022 were extracted from the Database of Comprehensive AIDS Control and Prevention of the Chinese Center for Disease Control and Prevention.The cases were categorized based on the initiation of cART timely or untimely.Logistic regression analysis was employed to identify the factors influencing the timeliness of cART initiation.Results A total of 15 896 cases of newly diagnosed HIV/AIDS from 2017 to 2022 were included in the analysis,with a mean age of 42.60±16.60 years.Among these cases,10 956(68.92％)received timely cART therapy.The proportions of cases receiving timely cART for each year from 2017 to 2022 were 61.44％(1 617/2 632),67.02％(1 831/2 732),70.52％(1 950/2 765),68.02％(1 706/2 508),73.58％(2 061/2 801),and 72.86％(1 791/2 458),respectively.Compared to patients who traveled across cities,were registered residents in other provinces,were diagnosed with latent HIV/AIDS,were single,had samples submitted from medical facilities,had an education level of primary school and below,or were male,those who only traveled within the city(OR=1.860,95％CI:1.718-2.014),had a registered residence in Anhui Province(OR=1.807,95％CI:1.496-2.181),were diagnosed with symptomatic AIDS(OR=1.706,95％CI:1.576-1.847),were married(OR=1.566,95％CI:1.409-1.741),were divorced or widowed(OR=1.356,95％CI:1.200-1.532),specifically tested during a medical consultation(OR=1.210,95％CI:1.117-1.312),had a high school education or above(OR=1.204,95％CI:1.069-1.356),or were female(OR=1.164,95％CI:1.041-1.302)were more likely to receive timely treatment.Conclusions The proportion of newly diagnosed HIV/AIDS cases receiving timely cART in Anhui Province showed an increasing trend.The key targets of the work include floating population,cases with registered residence in other provinces,unmarried and lower education groups.Efforts should focus on enhancing public education,improving treatment referral efficiency and quality,and enhancing the timeliness of cART initiation.
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