Combination antiretroviral therapy(cART)is currently recognized internationally as the most effective treatment for HIV/AIDS.However,it only inhibits viral replication without eradicating the virus.The curative success in the case of the"Berlin Patient"has propelled HIV/AIDS cure into a research hotspot and a novel therapeutic objective.Nonetheless,the majority of HIV/AIDS cure research is still in its early,and while it has brought increased hope for disease eradication,and also raised a host of ethical concerns.These concerns are particularly pronounced in the context of cART interruption(also known as analytic treatment interruption,ATI),which raises questions about participant risk and the validity of informed consent.This article examines several key issues in HIV/AIDS cure research,including the technical and societal risks,participant recruitment and informed consent,the hazards to non-direct research participants,and the use of martial metaphors in cure research discourse.Subsequently,the article proposes recommendations for the ethical governance of HIV/AIDS cure research.The aim is to promote the sound conduct of such studies under the guidance and regulation of ethical standards,thereby contributing to the advancement of curative endeavors in the field of HIV/AIDS.
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