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生殖器疱疹母婴传播所致疾病负担及防治研究进展

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生殖器疱疹可以通过母婴传播引起胎儿或新生儿的单纯疱疹病毒(HSV)感染,导致流产、死产、早产、新生儿疱疹、新生儿死亡等严重不良后果.目前,全球孕产妇生殖器疱疹及新生儿疱疹的危害与疾病负担日益受到关注.由于妊娠后期HSV感染的母婴传播风险很高,新生儿疱疹的预防主要取决于妊娠后期HSV感染的预防.本文综述了生殖器疱疹母婴传播所致疾病负担及防治研究进展,为生殖器疱疹母婴传播的防控提供参考.
Research progress on disease burden and prevention of mother-to-child transmission of genital herpes
Genital herpes can result in fetal or neonatal herpes simplex virus(HSV)infections through vertical transmission,leading to serious adverse outcomes such as miscarriage,stillbirth,preterm birth,neonatal herpes,and neonatal mortality.The harm and disease burden associated with maternal genital herpes and neonatal herpes are increasingly recognized globally.Due to the high risk of vertical transmission of HSV during late pregnancy,preventing HSV infection in the late stages of pregnancy is crucial for the prevention of neonatal herpes.This article reviews the research progress on the disease burden and prevention of mother-to-child transmission of genital herpes,and provides a reference for the prevention and control of mother-to-child transmission of genital herpes.

genital herpesmother-to-child transmissionneonatal herpesdisease burden

陈泽伟、岳晓丽、龚向东

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北京协和医学院/中国医学科学院/皮肤病医院/皮肤病研究所中国疾病预防控制中心性病控制中心性病流行病学室,南京 210042

生殖器疱疹 母婴传播 新生儿疱疹 疾病负担

中国医科院医学与健康科技创新工程项目

CIFMS-2021-I2M-1-001

2024

中国艾滋病性病
中国性病艾滋病防治协会

中国艾滋病性病

CSTPCD北大核心
影响因子:1.292
ISSN:1672-5662
年,卷(期):2024.30(5)
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