Laboratory proficiency testing results of CD4 count in China,2012-2023
Objective To understand the capacity of HIV testing laboratories for CD4 count in China,and to provide data reference for ensuring the quality of laboratory testing.Methods The results of the CD4 proficiency testing(PT)program organized by the National AIDS Reference Laboratory(NARL)from 2012 to 2023 were analyzed.Fisher's exact test was used to compare the good rates of different types of laboratories.Results From 2012 to 2023,the NARL received a total of 4 142 PT results for laboratory evaluation.Among the participating laboratories,the average annual participation rates in prefectural and municipal cities,the Center for Disease Control and Prevention(CDC),and western regions were 68.3％,87.8％,and 47.6％,respectively.A decreasing trend was observed in the proportion of laboratories with failing PT results(x2trend=19.4,P＜0.05),with operational errors being the main cause of unqualified results(73/73).Comparisons of good rates among different types of laboratories from 2012 to 2023 showed no statistically significant differences across different administrative regions.However,in 2012 and 2013,there were statistically significant differences in good rates among laboratories from different institution types(P＜0.05),with medical institution having lower good rates(71.4％and 73.9％)compared to CDCs(91.0％and 89.8％).In 2013,2019,and 2020,a statistically significant difference was observed in the good rate was observed among laboratories from different economic regions(P＜0.05).In 2013,laboratories in the eastern region had a lower good rate of 80.0％,while in 2019 and 2020,laboratories in the northeastern region had lower good rates of 83.3％and 72.7％,respectively.Conclusions From 2012 to 2023,laboratories participating in the NARL CD4 PT program were mainly from prefectural and municipal cities,CDCs,and mostly located in the western region.The overall CD4 count capacity of HIV testing laboratories in China was generally good and stable,while there is still a need to strengthen technical training for laboratory staff and focus on building and managing the quality of CD4 count capacity in laboratories in medical institutions and the northeast region.
NETL
NSTL
万方数据
