Epidemiological characteristics of hepatitis C among community-based detoxification population in Shanghai
Objective To understand the epidemiological characteristics of hepatitis C virus(HCV)among community-based detoxification populations in Shanghai,and to provide scientific evidence for optimizing prevention and control strategies for HCV in this population.Methods A multi-stage stratified cluster sampling method was used to conduct a questionnaire survey among community-based detoxification individuals in Xuhui District,Jing'an District,and Baoshan District of Shanghai in 2022.Data on general demographic information,history of drug use,family income,medical insurance,and willingness for HCV treatment were collected.Blood samples were collected for HCV antibody testing,nucleic acid testing,and genotyping.Results A total of 1 590 community-based detoxifica-tion individuals were included in the survey.The HCV antibody positive rate was 30.9％(492 individuals),and the nucleic acid positive rate was 19.4％(308 individuals).The dominant genotypes were 6n(25.7％),6a(18.0％),and 3a(16.9％).Willingness for HCV treatment was 70.7％(1 124 individuals).The survey indicated that female,age group of 45-59 years,education level of junior high school or below,a history of opiate drug use,and a history of injecting drug use were risk factors for HCV infection among community-based detoxification individuals.Factors promoting treatment willingness included age group of 44 years or below,being married or cohabiting,a history of amphetamine-type stimulant drug use,higher monthly family income per capita,and having personal health insurance.Conclusions The prevalence of HCV infection and treatment willingness among the community-based detoxification population in Shanghai is relatively high.However,limited income levels and inadequate medical insurance coverage may affect the actual implementation of treatment.It is recommended that targeted prevention and control measures for HCV should be implemented in high-risk populations,such as women,middle-aged and elderly individuals,those with low education levels,a history of opiate drug use,and a history of injecting drug use.Exploring payment models such as community diagnosis and treatment and family support can help eliminate HCV.
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