Combination antiretroviral therapy(cART)can effectively suppress HIV replication and greatly prolong the lifespan of people living with HIV(PLWH).However,non-AIDS-related comorbidities are increasing and now represent the primary cause of mortality in PLWH.In recent years,the concomitant occurrence of non-alcoholic fatty liver disease(NAFLD)in PLWH has become the research focus.The occurrence of NAFLD in PLWH is influenced by multiple factors,including age and gender.Screening and diagnosis rely on imaging and serum tests,while treatment approaches are similar to those for HIV-negative individuals(including diet and exercise,management of comorbidities,and liver protection).Additionally,optimization of cART regimens is necessary.This article aims to provide a comprehensive review of the latest research advancements in the epidemiology,diagnosis,and treatment of HIV infection with nonalcoholic fatty liver disease to enhance the level of diagnosis and management.
关键词
艾滋病病毒感染者/艾滋病患者/非酒精性脂肪肝病/流行病学/危险因素
Key words
people living with HIV(PLWH)/non-alcoholic fatty liver disease(NAFLD)/epidemiology/risk factors
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