Objective This study utilized factor analysis combined with cluster analysis to examine the distribution and characteristics of traditional Chinese medicine(TCM)syndromes in AIDS patients classified as immunological non-responders(INR).Methods The TCM questionnaire information of 378 patients was collected,and the frequency of all symptoms and signs was calculated.The main four-examination information was included in the factor analysis matrix to extract the common factor.These factors were then used as variables for systematic cluster analysis.Results Factor analysis identified nine common factors with a cumulative contribution rate of 89.74％.Cluster analysis divided these into four groups,corresponding to four types of TCM syndromes:dual deficiency of the lung-spleen syndrome(33.07％),which included common factors F3,F8,and F9;heart-liver blood deficiency syndrome(10.85％),which included common factor Fl;liver-kidney essence deficiency syndrome(37.83％),which included common factors F4 and F7;and syndrome of depressed liver qi transforming into fire(18.25％),which included common factors F2,F5,and F6.Conclusions The disease manifestations of AIDS INR predominantly affect the five viscera,typically presenting as either a deficiency pattern or a deficiency-excess complex.The primary TCM syndromes identified include dual deficiency of the lung-spleen syndrome,heart-liver blood deficiency syndrome,liver-kidney essence deficiency syndrome,and syndrome of depressed liver qi transforming into fire.
关键词
艾滋病免疫重建不全/中医证型/证素/因子分析/聚类分析
Key words
AIDS immunological non-responder(INR)/traditional Chinese medicine(TCM)syndrome types/syndrome elements/factor analysis/cluster analysis
维普
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