首页|HIV/AIDS患者传播风险评估与分类干预策略实施前后效果分析

HIV/AIDS患者传播风险评估与分类干预策略实施前后效果分析

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目的 评价HIV/AIDS患者传播风险评估与分类干预策略在台州的实施效果.方法 对现住址为台州市的HIV/AIDS患者进行传播风险评估,开展为期1年的随访干预工作,随访期间针对不同传播风险的患者实施不同的干预策略,分析分类干预前后HIV/AIDS患者传播风险并进行干预效果评估.结果 研究共纳入4 329例HIV/AIDS患者,经过1年的分类干预,172例(3.97%)HIV/AIDS患者被排除.高和极高传播风险患者从17.37%(722/4 157)降低至9.62%(400/4 157),分类干预前后差异有统计学意义(x2=106.827,P<0.001),不同性别、年龄组(除20岁以下年龄组)、职业、文化程度、婚姻状况、基线调查时病程、传播途径(除吸毒及其他传播途径)、检出途径患者的高和极高传播风险比例在分类干预后均显著下降(P<0.05).通过风险评估与分类管理策略的实施,高和极高传播风险艾滋病患者接受cART比例从82.41%上升到86.84%(x2=5.451,P<0.05);现症梅毒阳性比例从7.43%下降到2.77%(x2=15.712,P<0.05).结论 艾滋病患者传播风险评估与分类干预策略在台州实施初见成效,能够有效降低HIV/AIDS患者中高和极高传播风险比例,提高HIV/AIDS患者中高和极高传播风险者cART比例,降低现症梅毒阳性比例.应进一步优化HIV/AIDS患者风险评估与分类干预管理策略,降低病毒载量,有效控制传染源的二代传播.
Evaluation of the effectiveness of transmission risk assessment and classified intervention strategies before and after implementation among HIV/AIDS patients
Objective To evaluate the effectiveness of the implementation of transmission risk assessment and classified intervention among HIV/AIDS patients in Taizhou.Methods Risk assessments were carried out for HIV/AIDS patients with current addresses in Taizhou,followed by a one-year follow-up intervention.During the follow-up period,different intervention strategies were implemented based on different levels of transmission risk.The transmission risk of AIDS cases before and after the classified intervention was analyzed and the intervention effect was evaluated.Results A total of 4 329 patients with HIV/AIDS were.included in the study.After one year of classified interventions,172 patients(3.97%)were excluded.The proportion of patients at high or very high transmission risk decreased from 17.37%(722/4 157)to 9.62%(400/4 157),and the difference before and after classified intervention was statistically significant(x2=106.827,P<0.001).Significant reductions in the proportion of patients at high or very high transmission risk were observed across different sexes,age groups(except those under 20 years old),occupations,education levels,marital status,durations of disease at baseline,transmission routes(except drug abuse and other transmission routes),and detection routes(P<0.05).Implementation of risk assessment and classified management strategies led to an increase in the proportion of patients at high or very high transmission risk receiving combination antiretroviral therapy(cART)from 82.41%to 86.84%(x2=5.451,P<0.05).The proportion of syphilis positive patients decreased from 7.43%to 2.77%(x2=15.712,P<0.05).Conclusions The implementation of HIV/AIDS transmission risk assessment and classified intervention has achieved initial results in Taizhou,which can effectively reduce the proportion of HIV/AIDS patients at high or very high transmission risk,increase the proportion of those receiving cART,and reduce the proportion of syphilis positive patients.Risk assessment and classified intervention management strategies for HIV/AIDS patients should be further optimized to reduce viral load and effectively control the second-generation transmission of infection sources.

HIV/AIDSrisk assessmentclassified intervention strategy

王雅婷、汪剡灵、王婷婷、谢亚莉、沈伟伟、陈潇潇、刘星、何纳、林海江

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台州市疾病预防控制中心,浙江台州 318000

复旦大学公共卫生学院,上海 200032

艾滋病病毒感染者/艾滋病患者 风险评估 分类干预

浙江省自然科学基金台州市高层次人才特殊支持计划台州市科技计划项目

TGY23H260003TZ2022-224ywb113

2024

中国艾滋病性病
中国性病艾滋病防治协会

中国艾滋病性病

CSTPCD北大核心
影响因子:1.292
ISSN:1672-5662
年,卷(期):2024.30(9)
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