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HIV/AIDS患者孤独患病率的Meta分析

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目的 通过Meta分析系统评估HIV/AIDS患者孤独患病率.方法 检索了英文数据库(PubMed、Embase、Cochrane library、Web of Science)和中文数据库(中国知网、万方、维普)中的相关文献,检索时间截至2024年5月12日,纳入关于HIV/AIDS患者的孤独患病率的文献.使用R4.2.3进行分析,并通过亚组分析探讨可能的异质性来源.结果 最终纳入29篇文献,总样本量为15 056人.Meta分析结果显示,HIV/AIDS患者的孤独患病率为52.0%(95%CI:44.7%~59.2%).亚组分析结果显示,孤独患病率女性(46.0%,95%CI:35.0%~57.1%)高于男性(42.6%,95%CI:34.6%~50.5%);50~59岁人群(36.5%,95%CI:15.0%~58.1%)高于60岁及以上人群(33.2%,95%CI:23.9%~42.5%);调查时间在 2015 年前(63.1%,95%CI:49.8%~76.4%)高于 2015-2019 年(54.5%,95%CI:37.2%~71.8%)和2020-2022 年(38.5%,95%CI:28.4%~48.6%);独居人群(52.8%,95%CI:30.2%~75.3%)高于非独居人群(33.4%,95%CI:16.0%~50.8%);未婚人群(48.9%,95%CI:39.9%~57.9%)高于已婚人群(30.7%,95%CI:19.6%~41.8%);异性恋人群(41.5%,95%CI:28.1%~54.8%)高于同性恋人群(34.1%,95%CI:17.7%~50.5%)和双性恋人群(35.0%,95%CI:0~69.2%);抑郁患者(78.0%,95%CI:65.2%~90.7%)高于非抑郁患者(25.4%,95%CI:6.5%~44.3%).使用 UCLA-20评估的孤独患病率(61.2%,95%CI:44.1%~78.3%)高于其他评估方法,中国HIV/AIDS患者孤独患病率(58.6%,95%CI:41.5%~75.7%)高于其他国家.结论 HIV/AIDS患者的孤独患病率较高,尤其是在较年轻、女性、独居、未婚、异性恋和抑郁人群中.提示需要在HIV/AIDS患者中加强心理健康筛查和干预,密切关注以上重点人群,采取干预措施以改善其生活质量和健康结局.
Prevalence of loneliness among HIV/AIDS patients:a meta-analysis
Objective To systematically evaluate the prevalence of loneliness among patients with HIV/AIDS through a meta-analysis.Methods Relevant literature was retrieved from English(PubMed,Embase,Cochrane Library,and Web of Science)and Chinese databases[China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,VIP Chinese Journal Service Platform]up to May 12,2024.Studies reporting the prevalence of loneliness among patients with HIV/AIDS were included.The analysis was performed using R 4.2.3,incorporating a subgroup analysis to explore potential sources of heterogeneity.Results A total of 29 studies were included,comprising a sample size of 15 056 patients with HIV/AIDS.The meta-analysis revealed that the prevalence of loneliness among patients with HIV/AIDS was 52.0%(95%CI:44.7%-59.2%).Subgroup analysis revealed a higher prevalence of loneliness among females(46.0%,95%CI:35.0%-57.1%)than among males(42.6%,95%CI:34.6%-50.5%).Patients aged 50-59 years(36.5%,95%CI:15.0%-58.1%)exhibited a higher prevalence than did those aged 60 and above(33.2%,95%CI:23.9%-42.5%).Studies conducted before 2015 reported a higher prevalence(63.1%,95%CI:49.8%-76.4%)compared to that reported in those from 2015-2019(54.5%,95%CI:37.2%-71.8%)and 2020-2022(38.5%,95%CI:28.4%-48.6%).Individuals living alone showed higher loneliness rates(52.8%,95%CI:30.2%-75.3%)than did those not living alone(33.4%,95%CI:16.0%-50.8%).Unmarried individuals reported higher prevalence of loneliness(48.9%,95%CI:39.9%-57.9%)compared to that in married individuals(30.7%,95%CI:19.6%-41.8%).Heterosexual individuals exhibited a higher prevalence(41.5%,95%CI:28.1%-54.8%)than did homosexuals(34.1%,95%CI:17.7%-50.5%)and bisexual individuals(35.0%,95%CI:0-69.2%).Patients with depression reported a higher loneliness rate(78.0%,95%CI:65.2%-90.7%)than that of non-depressed patients(25.4%,95%CI:6.5%-44.3%).Loneliness assessed using the UCLA-20 scale showed a prevalence of 61.2%(95%CI:44.1%-78.3%),which was higher than that assessed by other methods.Additionally,the prevalence among Chinese HIV/AIDS patients was 58.6%(95%CI:41.5%-75.7%),exceeding rates in other countries.Conclusions The prevalence of loneliness among HIV/AIDS patients is relatively high,particularly among younger,female,single,living alone,heterosexual,and depressed individuals.These findings underscore the urgent need for enhanced mental health screening and interventions targeting these key populations to improve their quality of life and health outcomes.

HIV/AIDSprevalence of lonelinessmeta-analysismental health

詹沈澳、翟文静、黄钰、孔泉、傅更锋、羊海涛

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东南大学公共卫生学院,南京 210009

南京医科大学公共卫生学院,南京 211166

江苏省疾病预防控制中心,南京 210009

艾滋病病毒感染者/艾滋病患者 孤独患病率 Meta分析 心理健康

2024

中国艾滋病性病
中国性病艾滋病防治协会

中国艾滋病性病

CSTPCD北大核心
影响因子:1.292
ISSN:1672-5662
年,卷(期):2024.30(11)