Dengue fever,caused by the Dengue virus(DENV)and transmitted by mosquitoes,is increasingly recognized as a significant public health challenge worldwide.Although research on Dengue vaccines is processing,several challenges remain,including unclear protective standards and antibody-dependent enhancement.Current DNA vaccines are highly expected but face limitations in application.Future research should focus on deepening the understanding of immune responses,improving the cross-protection ability of vaccines,and developing more precise vaccination strategies.Additionally,differentiated vaccination strategies targeting different age groups and regions,as well as the development of novel vaccine platforms such as mRNA vaccines,provide new possibilities for dengue prevention and control.Overall,dengue virus vaccine research plays a key role in addressing global public health challenges and necessitating continued attention needs to immune mechanisms,cross-protection capabilities,and vaccination strategies to provide scientific support for global dengue prevention and control.
维普
万方数据