首页|Recent advances in understanding T cell activation and exhaustion during HBV infection
Recent advances in understanding T cell activation and exhaustion during HBV infection
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NETL
NSTL
万方数据
Chronic hepatitis B virus(HBV)infection remains a major public health concern globally,and T cell responses are widely believed to play a pivotal role in mediating HBV clearance.Accordingly,research on the characteristics of HBV-specific T cell responses,from activation to exhaustion,has advanced rapidly.Here,we summarize recent developments in characterizing T cell immunity in HBV infection by reviewing basic and clinical research pub-lished in the last five years.We provide a comprehensive summary of the mechanisms that induce effective anti-HBV T cell immunity,as well as the latest developments in understanding T cell dysfunction in chronic HBV infection.Furthermore,we briefly discuss current novel treatment strategies aimed at restoring anti-HBV T cell responses.
Hepatitis B virus(HBV)T cellImmune therapy
Lu Wang、Xiaoqing Zeng、Zida Wang、Ling Fang、Jia Liu
展开 >
Department of Infectious Diseases,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430022,China
Joint International Laboratory of Infection and Immunity,Huazhong University of Science and Technology,Wuhan,430022,China
Central Sterile Supply Department,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430022,China
National Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaNational Scientific and Technological Major Project of ChinaSino-German Virtual Institute for Viral Immunology
NETL
NSTL
万方数据
