Objective Small-vessel coronary artery disease in patients with clinical characteristics and treatment measures stent implantation using small ,the effect is to explore,analyze,and accumulated clinical experience.Methods Randomly selected hospital from March 2007 to February 2011 were treated coronary artery stenos is Total 240 cases,of which a small group of 96 patients the stent implementation of small vessel stent implantation;major vascular stent group 144 patients,the implementa-tion of major vascular stent implantation;between the two groups of patients surgical methods ,clinical features and prognosis compare similarities and differences .Results The composition of small vessel stunting power of 97.78%,major vascular stents composed of 99.04%power;small vessel stent in patients with a high incidence of typeⅡ diabetes group in large vessels;Complications during surgery and during follow -up the prognosis between the two groups was not statistically significant differences . Conclusion The success rate of stent implantation ,prognosis,small group and large vessel stent stents were not statistically significant between the groups ,the differences can be safe in the clinical application of small blood vessels to treat coronary artery stenos is treatment to improve the patient's quality of life.