摘要
目的：探讨复方小儿退热栓治疗小儿感冒发热的疗效和安全性。方法将100例小儿感冒发热患者按照抽签方法随机地均分为对照组与观察组，每组各为50例。对照组给予尼美舒利分散片进行治疗，观察组给予复方小儿退热栓进行治疗。比较两组临床治疗疗效、平均退热时间、治疗前后平均体温以及不良反应发生率。结果①观察组临床治疗总有效率为98．00％，显著小于对照组（78．00％），两组相比，差异具有统计学意义；②对照组平均退热时间为（2．39±0．37）d，显著大于观察组退热时间（1．25±0．16）d，两组相比，差异具有统计学意义；两组治疗前后体温差异均具有统计学意义，两组治疗后体温差异无统计学意义）；③对照组不良反应发生率为20．00％，显著大于观察组（10．00％）。结论复方小儿退热栓治疗小儿感冒发热的临床疗效显著，安全性高，值得在临床上加以推广并应用。
Abstract
Objective To investigate the treatment of children with antipyretic suppository compound pediatric cold and fever of efficacy and safety .Methods 100 cases of pediatric patients with cold and fever were randomly divided into control group and observation group in accordance with the balloting method ,and each group was 50 cases.Control group was given nimesulide dispersible tablets for treatment ,the observation group was given compound to treat pediatric antipyretic suppository . Clinical efficacy was compared,the average cooling time,average body temperature before and after treatment,and incidence of adverse reactions.Results ①clinical ob-servation group total effective rate was 98.00%,significantly lower than the control group(78.00%),the two groups,the difference was statistically significant;② the control group,the average cooling time was(2.39 ±0.37)d,was significantly greater than the observed cooling time group [(1.25 ±0.16)d],the two groups,the differ-ence was statistically significant;temperature difference between the two groups before and after treatment were statistically significance ,body temperature after treatment in both groups showed no significant difference;③ control group of adverse reactions was 20.00%,which was significantly greater than the observation group (10. 00%) .Conclusion Compound pediatric antipyretic suppository treatment of children with cold and fever of significant clinical efficacy ,safety,deserve to be promoted in clinical and applied.
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