Objective to patients with rhubarb enema adjuvant treatment of acute drug poisoning ,discussion and analysis of the clinical effect of the treatment . Methods for monitoring and treatment control group routine;the test group based on the treatment in control group,were treated with rhubarb enematherapy.Results in the trial group,the cure rate was 84%was higher than that of the control group was 56%,significantly,with statistical significance(P<0.05).Conclusion clinically, were treated with rhubarb enema therapy on acute drug poisoning,effectively alleviate symptoms,decrease mortality,improve the therapeutic effect and the quality of life of the patients.