Objective To explore the analysis of children's pneumonia treated by injection of the clinical effect of treatment with azithromycin .92 cases of children patients with pneumonia Methods In our hospital in 2012 March-2013 year in February as the object of study .Results The clinical patients with pneumonia in A group of children with efficiency was higher than that in group B(P<0.01);group A patients with adverse reaction rate compared with B patients without significant difference (P<0.01).Conclusion Injection in the treatment of children's pneumonia with azithromycin is effective and safe.