Objective To study the clinical success rate and matters needing attention of closed biopsy implementation of pleural diseases .Methods 140 patients with different causes of pleural effusion,the implementation of transthoracic Zhao closed pleural biopsy;pleural tissues were taken by 10%formalin fixed and pathological examination after,and make relevant cytology and conventional effusion examination.Results The patients selected 92.5%were successful,41 patients were diagnosed as tuberculosis pleurisy,68 cases with clinical diagnosis,the coincidence rate was 60.2%(41/68),36 cases of malignant tumor,47 cases with clinical diagnosis,the coinci-dence rate was 76.5%(36/47),the positive rate of pathological diagnosis of 61.3% patients with CT,via thoracoscope and guide,by percutaneous lung puncture and exploratory thoracotomy confirmed 18 cases of malignant tumor,29 cases of tuberculous pleurisy,6 cases of pleural effusion and 2 patients with connective tissue disease, postoperative complications were found in 6 cases,were not seen in all the patients with pneumothorax.Conclusion Percutaneous needle biopsy of pleura with relatively simple operation,without serious complications,low risk,less trauma and contraindications advantages in clinical.
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