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早期肠内营养预防重型颅脑损伤并发应激性溃疡的观察

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目的:探讨早期肠内营养在预防重型颅脑损伤并发应激性溃疡的作用。方法将164例重型颅脑损伤患者随机分为治疗组和对照组,对照组采用重型颅脑损伤常规治疗和静脉用奥美拉唑40mg加入0.9%生理盐水100ml中静脉滴注,2次/d,而治疗组所有患者发病后24h上鼻胃管,48h内给予早期肠内营养(清流食+能全力),以后逐日增量。结果治疗组应激性溃疡发生率9.7%,死亡率14.6%。对照组为28%,死亡率32.9%,两组差异显著。结论应激性溃疡治疗的关键是早期预防,早期予以肠内营养,能有效预防重型颅脑损伤并发应激性溃疡,降低病死率。
Purpose Our purpose is to study the effects of early enteral nutrition on severe brain injuries with stress ulcer .Methods 164 patients with severe brain injury were randomly divided into treatment group and control group .Then control group was given a routine therapy for severe brain injury patients and a 2 times per day intravenous injection of a solution prepared by dissolving 40 mg of omeprazole in 100 ml of 0.9% saline solution.The treatment group was all treated with a nasogastric tube soon after the morbidity of the disease within 24 h and was give early enteral nutrition(clear liquid diet +enteral nutritional suspension)within 48 h.Then the dos-age increase day by day in the future.Results The stress ulcer incidence of the treatment group was 9.7% and the death rate was14.6%.While the control group were 28% and 32.9% respectively.An obvious difference was found in these two groups.Conclusion The key to the stress ulcer treatment is an early prevention and giving an early enteral nutrition which can effectively prevent the severe brain injury with stress ulcer and reduce the fatality rate .

Severe brain injuryStress ulcerEnteral nutrition

赵劲松、任道梅

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湖北省枣阳市新型农村合作医疗管理办公室,湖北 枣阳 441200

湖北省枣阳市第一人民医院,湖北 枣阳 441200

重型颅脑损伤 应激性溃疡 肠内营养

2014

中国保健营养(下旬刊)
全国卫生产业企业管理协会

中国保健营养(下旬刊)

ISSN:1004-7484
年,卷(期):2014.(5)
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