Objective To explore the nursing intervention on chronic atrophic gastritis of precancerous lesions treatment .Methods chronic atrophic gastritis of pre-cancerous lesions from September 2012 to September 2013 in our hospital treated 80 cases were divided into control group and observation group ,each patient was 40 pa-tients in the control group to implement routine care ,observation group practice nursing intervention on this basis ,comparing the two groups of care results .Results After treatment,the effective rate was 95.0% in the observation group,the control group was 65.0% in the observation group than the control group,P <0.05,significant difference.Conclusion After the implementation of nursing interventions,the psychological state of the patient to maintain a good,reasonable adjustment in the diet,high adherence to treatment,rehabilitation,the patient's obvious,worthy of promotion.