摘要
目的：探讨血清Cys C在肝病患者肾功能早期损伤中的诊断价值。方法测定291例肝病患者和40例健康者血清Cys C、ALT、AST、γ-GT和Cr的浓度并进行比较分析。结果各肝病组血清Cr浓度与对照组差异无统计学意义（P＞0．05）。各肝病组患者血清ALT、AST、γ-GT高于健康对照组（P＜0．05）。代偿期肝硬化、非代偿期肝硬化、原发性肝癌患者血清Cys C均高于慢性乙肝组、慢性丙肝组和健康对照组，非代偿期肝硬化组血清Cys C高于代偿期肝硬化组（P＜0．05）。结论血清胱抑素C是预测肝病患者肾功能早期损伤的良好指标。
Abstract
Objective To discuss the diagnostic value of serum Cys C for renal early injury in patients with liver diseases .Method Serum Cys C,ALT,AST,γ-GT,Cr were determined and analyzed comparatively for 291 cases of liver disease patients and 40 healthy subjects.Results Serum Cr concentration in each liver disease group and the control group showed no significant difference(P>0.05).ALT,AST,γ-GT in each liver disease group was higher than that in control group(P<0.05). Serum Cys C was higher in compensated cirrhosis,decompensate cirrhosis and primary liver cancer than that in chronic hepatitis B ,chronic hepatitis C group and control group.Serum Cys C in decompensate cirrhosis group was higher than that in compensatory cirrhosis group(P<0.05).Conclusion Serum cystatin C is a good indicator for predicting renal early injury in patients with liver diseases .
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万方数据