首页|绝经后妊娠滋养细胞疾病64例临床分析

绝经后妊娠滋养细胞疾病64例临床分析

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目的:探讨绝经后妊娠滋养细胞疾病( GTD)的临床特点及其诊断和治疗。方法回顾性分析我院自2002年至2012年收治的64例绝经后妊娠滋养细胞疾病患者的临床资料。结果患者年龄50-58岁;绒毛膜癌30例,部分性葡萄胎34例;30例末次妊娠性质为流产,34例为葡萄胎;发病距末次妊娠时间3-21年;绝经年限1-4年;主诉均为绝经后阴道流血;有11例行血清β-HCG检查并发现异常;64例患者均接受了化疗,其中17例行全子宫双附件切除术。30例绒毛膜癌患者中,26例部分缓解后失访,2例完全缓解后随访19个月无瘤生存。结论绝经后 GTD虽然少见,但这些病例提醒我们对绝经后阴道流血的患者仍应想到有妊娠滋养细胞疾病的可能。一旦诊断为GID,应及早进行化疗,手术切除全子宫及双附件是很必要的。
Postmenopausal Gravid Trophocyte Diseases,64 cases of Clinical Analysis
Objective To investigate the postmenopausal gravid trophocyte diseases(GTD)clinical characteristic and diagnosis and treatment.Methods A retro-spective analysis of our hospital from 2002 to 2012 treated 64 cases of patients with postmenopausal gravid trophocyte diseases.Results The patients age 5 o-58 years old;Choriocarcinoma 30 cases,partial hydatidiform mole 34 cases;30 cases of the last pregnancy properties for abortion,34 cases of hydatidiform mole;At the end of the disease from pregnancy time 3-21 years;1-4 years duration ofmenopause;Chief complaint of postmenopausal vaginal bleeding;11 routine serum kind guide-HCG in-spection and found abnormal;All 64 patients received chemotherapy,total 17 underwent hysterectomy double adnexectomy.In 30 patients with choriocarcinoma,26 pa-tients after partial lost to follow -up,2 cases of complete remission after 19 months of follow-up disease-free survival.Conclusion The postmenopausal GTD,although rare,these cases remind us in patients with postmenopausal vaginal bleeding should still thinking may have gravid trophocyte diseases .Once diagnosed with GID,early chemotherapy,surgical removal of the uterus and the double appendix is necessary.

After menopauseGravid trophocyte diseasesDiagnosistreatment

刘恋

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湖北省荆门市康复医院妇产科,湖北 荆门 448000

绝经后 妊娠滋养细胞疾病 诊断 治疗

2014

中国保健营养(下旬刊)
全国卫生产业企业管理协会

中国保健营养(下旬刊)

ISSN:1004-7484
年,卷(期):2014.(6)
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