Objective To evaluate anti-interference ability of SIEMENS ADVIA2400 biochemical analyzer.Methods Using Spss and Excellsoftware according to CLSI(American Laboratory Standards Committee)EP7-A2 EP9-A2 document to test 18 different wavelengths projects(total protein、 albumin、 prealbumin et al.)of anti-interference ability with different methods.Results There are significant differences(P<0.005)of these projects include β2 -microglobulin 、uric acid(UA)in mild lipemia interference;there is differences(P<0.05)of Albumin(ALB)in mild lipemia interference;there is no significant difference(P>0.05)of these projects in-clude alanine aminotransferase(ALT)、aspartate aminotransferase(AST)、alkaline phosphatase(AKP)、 γ-glutamyl transferase(GGT)、total bile acid(TBA)、urea (BUN)、creatinine(CREA)、 lactate dehydrogenase(LDH)、creatine kinase(CK)、glucose(GLU)、calcium(CA)and amylase(AMS)at different concentrations lipemia interference;Interference project linear analysis were tested for linearity With the exception of PA .Conclusion SIEMENS biochemical analyzer ADVIA2400 dilution mode is used,the different methodologies of specimen and reagent proportion has bigger difference to the anti -interference ability of the blood lipid;the rate method is better than the end-point method and the Latex-enhanced immunoturbidimetric method is superior to the immune turbidimetric method .
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