Objective To study the high in the treatment of neonatal bilirubin concentration in the process of main application of wormwood Zhi yellow with blue light therapy method and effect.Methods Randomly choose between December 2011 and December 2011,our hospital in 113 newborn children with high bilirubin as the research object,for all children with clinical data were analyzed retrospectively,all patients were divided into observation group(57 cases)and control group(56 cases), to control the blu-ray according to illuminate and keeping the purge,oxygen and other foundation treatment methods.Observation group based method was given and wormwood Zhi yellow with blue light therapy.Comparative analysis of two groups of patients before and after treatment serum total bilirubin changes .Results Two groups of patients before treatment the serum total bilirubin comparative difference was not significant(P>0.05),there is no statistical significance.