首页|绝经前后女性子宫内膜癌178例临床病例分析

绝经前后女性子宫内膜癌178例临床病例分析

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目的:探讨绝经前后女性子宫内膜癌患者的临床病理特征、手术方式、预后等方面的相关因素、异同点。方法将本院2000年1月---2013年12月收治并确诊为子宫内膜癌的178例患者分为两组,绝经前组86例,绝经后组92例,并回顾分析两组患者的确诊时间,发病病理类型、临床病理特征、CA125、雌孕激素受体( ER、PR)等在绝经前后的同异点。结果绝经前、绝经后患者出现临床症状至确诊时间、糖尿病及合并高血压发病率差异有统计学意义( P<0.05);绝经前、绝经后患者行广泛子宫切除术和腹式全子宫切除术例数、CA125差异、病理特点(病理类型、深肌层浸润、淋巴转移、细胞分化程度、附件受累、宫颈受累、ER及PR阳性率)、5年存活率等无统计学意义(P>0.05)。结论绝经前后子宫内膜癌预后相似:均以不规则阴道流血为主要临床表现;且I型内膜癌占绝绝大多数;重视绝经前妇女的不规则阴道流血是早期诊断女性子宫内膜癌的关键,绝经后患者也应积极诊断治疗。
Objective To investigate the premenopausal and postmenopausal women with endometrial cancer clinical and pathological features,operation mode,the prognosis related factors,similarities and differences.Methods 178 cases of patients in the hospital from 2010 to 2013 were diagnosed as endometrial carcinoma and di-vided into two groups,86 cases of premenopausal group and postmenopausal group,92 cases were diagnosed,analysis time of two groups of patients and incidence of re-view,pathological type,clinical and pathological features,CA125,estrogen and progesterone receptor(ER,PR)in different points before and after menopause.Results Premenopause and postmenopausal patients clinical symptoms to diagnosis 、diabetes and hypertension rate was significant(P<0.05);before menopause,postmenopausal patients underwent radical hysterectomy and Tran abdominal hysterectomy、CA125 、postmenopausal (pathological type,depth of myometrial invasion,lymph node metas-tasis,the degree of cell differentiation,accessories are tired,cervical involvement,ER and PR positive rate comparison)、5 year survival rate were not significant difference (P>0.05).Conclusion Premenopausal and postmenopausal endometrial carcinoma prognosis similar:the irregular vaginal bleeding were the main clinical manifesta-tions;and all for I type endometrial cancer accounts for the vast majority of attention;irregular vaginal bleeding in premenopausal women is the key to early diagnosis of endometrial cancer in women,postmenopausal patients should also be positive diagnosis and treatment.

Endometrial neoplasmsPremenopausePoslmenopause

李凤茹

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吉林省四平市梨树县妇幼保健院,吉林 梨树 136500

子宫内膜癌 绝经前期 绝经后期

2014

中国保健营养(下旬刊)
全国卫生产业企业管理协会

中国保健营养(下旬刊)

ISSN:1004-7484
年,卷(期):2014.(6)
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