Objective:Through observing the effection of Ampicillin Na on the intestinal flora of mice,so as to provide the reference data for the correct use of Ampicillin Na on the study work.Methods:The mice in study groups were continuous lavaged 22.4g/kg doses of Ampicillin Na 3days and 5days,then test the number of bacillus,enterococci,lactobacillus and bifidobacterium in rectal of mice after stop giving Ampicillin Na 1,3,7,10,15th days. Results:The Ampicillin Na treatment groups all can cause mice intestinal dysbacteriosis,and longer group difficult to get well .Conclusion:Giving mice 22.4g/kg doses Ampicillin Na can be used in the preparation of mice intestinal dysbacteriosis model.
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