Objective:To analyze the functional changes of T lymphocyte subsets with Concurrent chemoradiotherapy of CAF chemotherapy in different doxorubicin dose for advanced breast cancer and its relationship with the disease. Methods:using monoclonal antibody by indirect immunofluorescence to detect T lymphocyte subsets in the treatment of patients with advanced breast cancer. Results: CAF chemotherapy A group and B group compared with the index of T lymphocyte subsets were not significantly change, A group and B group of T lymphocytes in patients with advanced breast cancer and the indexes of subsets of C group were significantly decreased. Conclusion:cyclophosphamide (600mg/m2, the first 1,8 days), doxorubicin dose (40 mg/m2, first days), 5-fluorouracil (500mg/m2, first days), chemotherapy is the best solution to the synchronization on the CAF scheme. Can reduce the chemotherapy and radiation damage, improve the survival rate of wide application, suggestions.
In advanced breast cancerConcurrent chemoradiotherapyCAF chemotherapy
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