Objective:Col ecting 128 patients with Adenocarcinoma of the esophagogastric junction to detect the Snail protein expression,analyze the correlation between Snail expression and different clinic pathological characteristics and the effect of metastasis and prognosis, discussing the clinical significance.Methods:Col ecting clinical data and fol owing-up 128 samples.Adopting immunohistochemical method in detecting the condition of Snail protein;applying statistical analysis in analyzing the result.Results:1.Snail protein expression is closely related with pathological tissue differentiation, UICC clinical stage,the lower the differentiation or the higher the stage, the stronger the Snail protein expression (P﹤0.05).2.The overal survival rate of Snail protein in negative expression group is bet er than the positive (P=0.004). Conclusions:Snail protein is correlated to the metastasis of adenocarcinoma of esophagogastric junction.Patients with high Snail protein expression have unfavorable prognosis.
Adenocarcinoma of the esophagogastric junctionSnail proteinImmunohistochemistryneoplasm metastasisprognostic
NETL
NSTL
万方数据
