Objective:To study the clinical effect of triamcinolone acetonide injection in the treatment of patients with the implementation of chalazion. Methods: a total of 76 patients with tarsal cyst patients, randomly divided into treatment group and control group, each an average of 38 cases. Using prednisolone for the patients in the treatment group was treated with triamcinolone acetonide acetate; the patients in the treatment group. Results:the patients in the treatment group chalazion illness treatment was better than the control group; recovery time and treatment time was shorter than the control group. Conclusion:the application of triamcinolone acetonide acetate on patients with tarsal cyst implementation clinical effect of injection therapy is very obvious.