objective:to observe the effect of laparoscopic appendectomy appendicitis treatment in the clinical application. Methods: randomly selected from April 2012 to April 2013 in our hospital 97 cases of appendicitis patients as the research object, the treatment for patients with laparoscopic appendectomy for treatment, and the clinical therapeutic effect of effective analysis. Results: after surgical treatment, al patients were recovered and discharged, does not appear after abdominal cavity infection, such as abdominal bleeding or infection of incision, increase of complication. Conclusion: for patients with laparoscopic appendectomy appendicitis treatment, can effectively improve the disease clinical curative effect, shorten the operation time and hospital stay, reduce the postoperative complications, and help patients back to health as soon as possible.