Objective: To explore the clinical effect of neoadjuvant chemotherapy in preventing recurrence of ovarian cancer and the impact of serum tumor markers. Methods: According to a stratified randomization method, 82 cases of ovarian cancer patients were divided into the observation group and the control group in our hospital, the control group was given chemotherapy after surgery, the observation group was given chemotherapy before surgery, two groups of the clinical efficacy and serum levels of tumor markers were observed, fol ow-up 2-years, two groups of prognosis and quality of life were observed. Results: The observation group was significantly bet er than the control group in the clinical efficiency, the ideal rate of tumor cytoreductive and the serum levels of tumor markers, the difference was statistical y significant(P<0.05);fol ow-up 2-years, the observation group was significantly bet er than the control group in the 2-year survival, the disease-free interval and the quality of life, the difference was statistical y significant(P<0.05). Conclusion: Neoadjuvant chemotherapy can significantly improve the clinical efficacy and prolong survival, it has important clinical value in the improving quality of life and prevention of disease recurrence.
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